Four families of transgender youth and two doctors have challenged an Arkansas law that would prohibit healthcare professionals from providing or even referring transgender young people for medically necessary health care. The law would also bar any state funds or insurance coverage for gender-affirming health care for transgender people under 18, and it would allow private insurers to refuse to cover gender-affirming care for people of any age. The lawsuit, filed in federal court, alleges that House Bill 1570 is a violation of the U.S. Constitution.

Transgender South Carolinians and their families challenged a 2024 state law banning gender-affirming medical care for transgender youth and prohibiting any state funds from supporting access to gender-affirming medical care. South Carolina’s ban led to medical providers ending treatment for transgender patients regardless of age.

Transgender young adults and families with transgender youth, together with PFLAG National and GLMA, filed a federal legal challenge against a January 2025 executive order from the Trump administration directing federal agencies to withhold funds from medical providers and institutions that provide gender-affirming medical treatments for people under nineteen.

Four Hoosier families, joined by medical providers, are challenging an Indiana law passed in April 2023 barring access to gender-affirming care for transgender youth. Indiana is home to over 4,000 transgender adolescents and the health care targeted by this law is supported by the entire mainstream of the medical community.