The American Civil Liberties Union filed a request for precautionary measures with the Organization of American States' Inter-American Commission on Human Rights showing that the execution of John Winfield, scheduled for June 18, 2014 in the state of Missouri, will cause irreparable harm should it go forward. The ACLU asks that the executions be stayed until the IACHR can review and rule on the ACLU's petition that alleges Mr. Winfield's death sentence violates international law. On June 6, 2014, the IACHR granted ACLU request for precautionary measures against the United States and requested that "the Government of the United States to abstain from executing John Winfield until the IACHR has ruled on the merits of the individual petition filed on his behalf."

The American Civil Liberties Union filed a petition with the Organization of American States' Inter-American Commission on Human Rights showing that the upcoming executions by lethal injection in Missouri and Oklahoma will violate international law against cruel and unusual punishment, should they go forward. The ACLU asks that the executions be stopped until the IACHR can conduct independent investigations of the two cases.

A federal district court has ruled that a public college in Missouri must end its unconstitutional program of requiring all of its students—irrespective of their course of study—to submit to suspicionless drug-testing.

Kelly Glossip and Dennis Engelhard had been committed domestic partners for 15 years when Dennis, a Missouri State Trooper, was killed while responding to an accident on Christmas Day, 2009. Missouri offers survivor benefits to spouses of state troopers who are killed in the line of duty, but excludes committed same-sex partners from receiving those benefits.