The case concerns the constitutionality of a Mississippi law prohibiting abortions after the fifteenth week of pregnancy. The state used the case as a vehicle to ask the Supreme Court to take away the federal constitutional right to abortion it first recognized 50 years before in Roe v. Wade. On June 24, 2022, the Supreme Court of the United States accepted the state’s invitation and overturned Roe eliminating the federal constitutional right to abortion.

The ACLU, the Southern Poverty Law Center (SPLC), the Law Offices of Elizabeth Alexander, and the law firm of Covington & Burling LLP, filed a petition for class certification and expert reports for a federal lawsuit on behalf of prisoners at the East Mississippi Correctional Facility (EMCF). The lawsuit, which was filed in May 2013, describes the for-profit prison as hyper-violent, grotesquely filthy and dangerous. EMCF is operated "in a perpetual state of crisis" where prisoners are at "grave risk of death and loss of limbs." The facility, located in Meridian, Mississippi, is supposed to provide intensive treatment to the state's prisoners with serious psychiatric disabilities, many of whom are locked down in long-term solitary confinement.