The American Civil Liberties Union (ACLU), the National Center for Youth Law (NCYL), and the New York Civil Liberties Union filed a lawsuit to demand transparency from the Trump administration regarding its treatment of pregnant unaccompanied immigrant youth in federal immigration custody. The lawsuit seeks to enforce the ACLU and NCYL’s February 2025 Freedom of Information Act (FOIA) request for records and correspondence from the Office of Refugee Resettlement (ORR), which oversees the care and custody of unaccompanied immigrant youth until they are placed with a sponsor, usually a family member in the United States. The release of this information is important to monitor whether the Trump administration is ensuring that these marginalized young people have access to the full range of pregnancy-related care while in government custody, as is required by law.

Anti-abortion politicians in Louisiana filed a federal lawsuit seeking to impose a nationwide restriction on mail and pharmacy access to mifepristone, a safe and effective medication used in nearly two-thirds of U.S. abortions as well as for early miscarriage care. On May 1st, a federal appeals court granted Louisiana's request, throwing abortion access across the country into turmoil. On May 4th, the Supreme Court put that ruling on hold for one week, until May 11th, while it considers whether to block it for a longer period of time, restoring patients' ability to get mifepristone through telemedicine for now.

In December 2020, Ohio Governor Mike DeWine signed into law Senate Bill 27, a fetal tissue disposal requirement that mandates burial or cremation of all embryonic and fetal tissue from a procedural abortion, imposing severe burdens on patients and stigmatizing essential care. On January 31, 2022, an Ohio judge preliminarily enjoined the law, finding that the law likely violates the Ohio state constitution’s guarantees of due process and equal protection. The victory followed a previous April 5, 2021, preliminary injunction halting enforcement of the law, because compliance would have been impossible due to the Ohio Department of Health’s (ODH) failure to establish necessary rules and regulations. In April 2024, Plaintiffs filed a Second Amended Complaint, adding a claim that the law violated the newly established Right to Reproductive Freedom Amendment of the Ohio Constitution, and in August 2024 filed a 12(C) Motion for Judgment on the Pleadings, arguing that Senate Bill 27 is unconstitutional as a matter of law under that Amendment for discriminatorily targeting procedural abortion. In February 2025, the Hamilton County Court of Common Pleas agreed, granting the Motion for Judgement on the Pleadings and permanently enjoining enforcement of Senate Bill 27. In February 2026, the Ohio First District Court of Appeals upheld the trial court's permanent injunction, ruling that the requirements under Senate Bill 27 violate the state constitution's Reproductive Freedom Amendment, which took effect in December 2023 after being approved by voters. This lawsuit was filed by the American Civil Liberties Union, ACLU of Ohio, Planned Parenthood Federation of America, and Fanon Rucker of the Cochran Law Firm on behalf of Ohio abortion providers.

A group of Arizona advanced practice nurses filed a lawsuit challenging the state’s ban on the provision of abortion by trained advanced practice clinicians (APCs) such as nurse practitioners and certified nurse midwives. The lawsuit, brought on behalf of the nurses by the American Civil Liberties Union (ACLU), the ACLU of Arizona, and the law firm Papetti Samuels Weiss McKirgan LLP, argues that the APC ban violates Arizonans' constitutional right to abortion access, established by voters in 2024, by arbitrarily restricting their choice of provider and, more broadly, making abortion less available in the state.